TAS05567
TAS05567 is a potent and highly selective ATP-competitive inhibitor of Syk with an IC50 of 0.37 nM. It demonstrates selectivity, showing significant activity against only four other kinases (FLT3, JAK2, KDR, RET) in a broad panel. This inhibitor is a valuable tool for investigating Syk-dependent signaling pathways in both in vitro and in vivo immunological and oncological research contexts.
Product Specifications
CAS Number
1429038-15-2
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CC=1C=2C (=CN (C (C) (C) C) N2) C=C (NC=3C (C (N) =O) =NN=C (N[C@H]4[C@@H] (N) COCC4) N3) C1
Molecular Formula
C21H29N9O2
Molecular Weight
439.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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