HIF-2a-I2
TC-S 7009 is a potent, selective HIF-2α inhibitor (Kd: 81 nM) that disrupts heterodimerization and DNA binding, suppressing target gene expression. It is widely used in vitro and in vivo for research on renal cell carcinoma, pulmonary hypertension, and other HIF-2α-driven pathologies.
Product Specifications
CAS Number
1422955-31-4
Product Name Alternative
TC-S 7009
Field of Research
Cell Biology
Purity
>98%
Bioactivity
HIF-2 antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 35 mg/ml)
Smiles
[O-][N+] (=O) c1c (Nc2cc (F) cc (Cl) c2) ccc2nonc12
Molecular Formula
C12H6ClFN4O3
Molecular Weight
308.65
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (3-chloro-5-fluorophenyl) -4-nitro-2,1,3-benzoxadiazol-5-amine
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