TCO-NHS ester
TCO-NHS ester is an alkyl/ether linker used to construct PROTAC molecules for targeted protein degradation. It covalently links a target-binding ligand to an E3 ligase recruiter, enabling the study of protein function in both cellular and in vivo models via the ubiquitin-proteasome system.
Product Specifications
CAS Number
1191901-33-3
Product Name Alternative
PROTACLinker, PROTAC Linker, TCONHS ester, TCO-NHS ester, TCO NHS ester, Alkyl/ether
Field of Research
Pharmacology & Drug Discovery
Purity
96.48% (May vary between batches)
Solubility
DMSO:150 mg/mL (561.21 mM)
Smiles
O=C (OC1CCCC=CCC1) ON1C (=O) CCC1=O
Molecular Formula
C13H17NO5
Molecular Weight
267.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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