Tefinostat
Tefinostat (CHR-2845) is a selective HDAC inhibitor activated intracellularly by human carboxylesterase-1 (hCE-1) to CHR-2847, targeting monocytes and macrophages. Its antitumor activity is under investigation for leukemia and hematologic malignancies, supported by in vitro and in vivo research models.
Product Specifications
CAS Number
914382-60-8
Product Name Alternative
CHR 2845, CHR2845, CHR-2845, HDAC, Tefinostat
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
99.41% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.66 mM) ; DMSO:90 mg/mL (181.59 mM)
Smiles
ONC (=O) CCCCCCC (=O) Nc1ccc (CN[C@H] (C (=O) OC2CCCC2) c2ccccc2) cc1
Molecular Formula
C28H37N3O5
Molecular Weight
495.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
494237 100 µL
TNFRSF9 (Tumor Necrosis Factor Receptor Superfamily Member 9)
Sign In for Pricing
View Details K6300807 1.0 µg DNA
Ermp1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details