TRAF-STOP inhibitor 6877002
TRAF-STOP inhibitor 6877002 is a selective small molecule that disrupts the CD40-TRAF6 interaction. It has been shown in research to attenuate macrophage activation and proliferation in atherosclerotic plaques, as well as reduce leukocyte recruitment in relevant in vivo models of inflammation.
Product Specifications
CAS Number
433249-94-6
Product Name Alternative
TRAF-STOP inhibitor 6877002, NF-kB, NFkB, NFκB, NF-κB, CD40-TRAF6 inhibitor, CD40-TRAF6 interaction
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.65% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.92 mM) ; DMSO:112.5 mg/mL (447.64 mM)
Smiles
Cc1ccc (C) c (N\C=C\C (=O) c2ccccc2) c1
Molecular Formula
C17H17NO
Molecular Weight
251.32
Storage Conditions
-20°C
Notes
For research use only.
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