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TY-51469

TY-51469 is a potent and selective chymase inhibitor, exhibiting IC50 values of 0.4 nM for simian and 7.0 nM for human chymase. This small molecule is a valuable research tool for investigating chymase-related pathologies, such as fibrosis and inflammation, in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

603987-59-3

Product Name Alternative

Hamster chymase enzyme, Human chymase, TY51469, TY-51469, TY 51469, Simian chymase

Field of Research

Protein Biochemistry

Purity

98.89% (May vary between batches)

Solubility

DMSO:45 mg/mL (85.45 mM)

Smiles

Cc1c (sc2ccc (F) cc12) S (=O) (=O) Nc1ccc (cc1S (C) (=O) =O) -c1nc (cs1) C (O) =O

Molecular Formula

C20H15FN2O6S4

Molecular Weight

526.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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