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TZ9

TZ9 is a selective Rad6 inhibitor that blocks Rad6B-mediated histone H2A ubiquitination. This activity underlies its observed anticancer effects, including induction of cell cycle arrest and apoptosis in vitro, supporting its use in oncology research targeting DNA damage response pathways.

Product Specifications

CAS Number

1002789-86-7

Product Name Alternative

E2Enzyme, E3 Enzyme, E1 Enzyme, E1Enzyme, E1/E2/E3 Enzyme, E2 Enzyme, Apoptosis, E3Enzyme, TZ 9, TZ9, TZ-9

Field of Research

Cell Biology, Protein Biochemistry

Purity

99.69% (May vary between batches)

Solubility

DMSO:40 mg/mL (109.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.46 mM)

Smiles

Nc1nc (COC (=O) c2ccc (cc2) [N+] ([O-]) =O) nc (Nc2ccccc2) n1

Molecular Formula

C17H14N6O4

Molecular Weight

366.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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