TZ9
TZ9 is a selective Rad6 inhibitor that blocks Rad6B-mediated histone H2A ubiquitination. This activity underlies its observed anticancer effects, including induction of cell cycle arrest and apoptosis in vitro, supporting its use in oncology research targeting DNA damage response pathways.
Product Specifications
CAS Number
1002789-86-7
Product Name Alternative
E2Enzyme, E3 Enzyme, E1 Enzyme, E1Enzyme, E1/E2/E3 Enzyme, E2 Enzyme, Apoptosis, E3Enzyme, TZ 9, TZ9, TZ-9
Field of Research
Cell Biology, Protein Biochemistry
Purity
99.69% (May vary between batches)
Solubility
DMSO:40 mg/mL (109.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.46 mM)
Smiles
Nc1nc (COC (=O) c2ccc (cc2) [N+] ([O-]) =O) nc (Nc2ccccc2) n1
Molecular Formula
C17H14N6O4
Molecular Weight
366.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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