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Vafidemstat

Vafidemstat (ORY-2001) is an orally bioavailable, brain-penetrant small molecule that potently inhibits LSD1 and MAO-B. It is a research tool for investigating neurological disorders, with demonstrated utility in both in vitro assays and in vivo models of neurodegeneration and neuroinflammation.

Product Specifications

CAS Number

1357362-02-7

Product Name Alternative

Histone Demethylase, HistoneDemethylase, MAO-B, ORY2001, ORY-2001, ORY 2001, LSD1/MAO-B, LSD1, Vafidemstat

Field of Research

Epigenetics & Chromatin, Metabolism Research, Neuroscience

Purity

99.30% (May vary between batches)

Solubility

DMSO:30 mg/mL (89.18 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (9.81 mM)

Smiles

Nc1nnc (CN[C@@H]2C[C@H]2c2ccc (OCc3ccccc3) cc2) o1

Molecular Formula

C19H20N4O2

Molecular Weight

336.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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