Osteopontin/OPN, Human (HEK293, His)
Osteopontin/OPN is a secretory glycophosphoprotein belonging to the SIBLING family. It contains RGD sequences and phosphorylation sites and can bind to integrins αvβ3, α4β1 and CD44 receptors. Osteopontin/OPN regulates cell adhesion and migration through receptor-mediated regulation, activates MAPK/ERK and PI3K-AKT to promote tumor invasion, and upregulates TIMP-1/2 to inhibit MMPs and protect cartilage. Osteopontin/OPN can be used in the study of osteoarthritis, liver cancer, etc[1][2][3].
Product Specifications
Product Name Alternative
Osteopontin/OPN Protein, Human (HEK293, His), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/osteopontin-opn-protein-human-hek293-his.html
Purity
98.00
Smiles
Molecular Formula
6696 (Gene_ID) P10451-1 (I17-N314) (Accession)
Molecular Weight
Approximately 50-69 kDa due to the glycosylation
References & Citations
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Available Sizes
Frequently Asked Questions
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