Valspodar
Valspodar (PSC 833) is a potent and specific inhibitor of P-glycoprotein, functioning as a multidrug resistance (MDR) modulator. It is widely utilized in oncology research, particularly in both in vitro and in vivo studies of advanced epithelial ovarian cancer, to investigate chemosensitization and overcome drug resistance.
Product Specifications
CAS Number
121584-18-7
Product Name Alternative
Pgp, P-glycoprotein, PSC 833, PSC833, PSC-833, Valspodar
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
95.00% (May vary between batches)
Solubility
DMSO:90 mg/mL (74.1 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (2.72 mM)
Smiles
C\C=C\C[C@@H] (C) C (=O) [C@@H]1N (C) C (=O) [C@H] (C (C) C) N (C) C (=O) [C@H] (CC (C) C) N (C) C (=O) [C@H] (CC (C) C) N (C) C (=O) [C@@H] (C) NC (=O) [C@H] (C) NC (=O) [C@H] (CC (C) C) N (C) C (=O) [C@@H] (NC (=O) [C@H] (CC (C) C) N (C) C (=O) CN (C) C (=O) [C@@H] (NC1=O) C (C) C) C (C) C
Molecular Formula
C63H111N11O12
Molecular Weight
1214.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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