Auglurant
Auglurant is a potent and selective metabotropic glutamate receptor 5 (mGlu5) antagonist, exhibiting nanomolar IC50 values of 11 nM in rats and 14 nM in humans with suitable brain penetration. This profile supports its utility in preclinical research for investigating mGlu5's role in CNS disorders such as fragile X syndrome, anxiety, and depression.
Product Specifications
CAS Number
1396337-04-4
Field of Research
Neuroscience
Smiles
Cc1cc (Oc2cncnc2) cc (n1) C (=O) Nc1ccc (F) cn1
Molecular Formula
C16H12FN5O2
Molecular Weight
325.3
Storage Conditions
-20°C
Notes
For research use only.
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