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Auglurant

Auglurant is a potent and selective metabotropic glutamate receptor 5 (mGlu5) antagonist, exhibiting nanomolar IC50 values of 11 nM in rats and 14 nM in humans with suitable brain penetration. This profile supports its utility in preclinical research for investigating mGlu5's role in CNS disorders such as fragile X syndrome, anxiety, and depression.

Product Specifications

CAS Number

1396337-04-4

Field of Research

Neuroscience

Smiles

Cc1cc (Oc2cncnc2) cc (n1) C (=O) Nc1ccc (F) cn1

Molecular Formula

C16H12FN5O2

Molecular Weight

325.3

Storage Conditions

-20°C

Notes

For research use only.

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