VU0529331
VU0529331 is a small molecule activator of inwardly rectifying potassium (GIRK) channels, showing moderate selectivity. It activates GIRK2 homomeric and GIRK1/2 heteromeric channels with similar EC50 values (~5 μM) and is also effective on GIRK4 homomers. This tool compound is used in vitro to study GIRK channel physiology and their roles in neuronal and cardiac excitability.
Product Specifications
CAS Number
1286725-49-2
Field of Research
Pharmacology & Drug Discovery
Purity
99.99% (May vary between batches)
Smiles
O=C (C1=NC=CN=C1) N2CC3=NN (C4=CC=C (C (=C4) C) C) C (=C3C2) N5C=CC=C5
Molecular Formula
C22H20N6O
Molecular Weight
384.43
Storage Conditions
-20°C
Notes
For research use only.
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