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YUKA1

YUKA1 is a selective, cell-permeable KDM5A inhibitor (IC50=2.66 μM) that elevates cellular H3K4me3 levels. It suppresses cancer cell proliferation and impedes the development of drug resistance, making it a valuable chemical probe for epigenetic and oncology research in both cellular and animal models.

Product Specifications

CAS Number

708991-09-7

Product Name Alternative

KDM5A, KDM5C, HistoneDemethylase, Histone Demethylase, YUKA 1, YUKA1, YUKA-1

Field of Research

Epigenetics & Chromatin

Purity

99.59% (May vary between batches)

Solubility

DMSO:80 mg/mL (273.64 mM)

Smiles

S=C1NN=CN1NCC=2C=CC=C (OC) C2OCC=C

Molecular Formula

C13H16N4O2S

Molecular Weight

292.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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