NPS-2143
NPS-2143 (SB 262470A) is a potent and selective calcium-sensing receptor (CaSR) antagonist. It is widely used in biochemical and physiological research to investigate CaSR function in vitro and has been applied in animal models to study disorders of calcium homeostasis, such as hyperparathyroidism.
Product Specifications
CAS Number
284035-33-2
Product Name Alternative
SB262470, SB-262470, SB-262470A, SB 262470, SB 262470A, Calcium-sensing receptor, CaSR, CalciumChannel, Calcium Channel, Ca (2+) receptor, inhibit, NPS 2143, NPS2143, NPS-2143, Inhibitor
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
98.24% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CC (C) (Cc1ccc2ccccc2c1) NC[C@@H] (O) COc1cccc (Cl) c1C#N
Molecular Formula
C24H25ClN2O2
Molecular Weight
408.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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