Biotin-PEG3-SS-azide
Biotin-PEG3-SS-azide is a cleavable linker for constructing antibody-drug conjugates (ADCs) . Its disulfide bond enables intracellular payload release, while the PEG spacer enhances solubility. This reagent is widely used in ADC development for targeted cancer therapy research in both in vitro and in vivo models.
Product Specifications
CAS Number
2866429-93-6
Product Name Alternative
Cleavable, ADCLinker, ADC Linker, Biotin-PEG3-amido-SS-amido-azide, Biotin-PEG3-SS-azide
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
99.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.76 mM) ; DMSO:90 mg/mL (129.89 mM)
Smiles
C (CCCC (NCCOCCOCCOCCC (NCCSSCCC (NCCCN=[N+]=[N-]) =O) =O) =O) [C@H]1[C@@]2 ([C@] (CS1) (NC (=O) N2) [H]) [H]
Molecular Formula
C27H48N8O7S3
Molecular Weight
692.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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