Canagliflozin hemihydrate
Canagliflozin hemihydrate (TA-7284) is a selective SGLT2 inhibitor used in type 2 diabetes research. By blocking renal glucose reabsorption, it promotes significant urinary glucose excretion. This compound is widely applied in both in vitro binding assays and in vivo metabolic disease models to study glucose homeostasis and related pathways.
Product Specifications
CAS Number
928672-86-0
Product Name Alternative
Canagliflozin Hemihydrate, Canagliflozin, JNJ 28431754, JNJ-28431754, JNJ28431754, TA 7284, TA-7284, TA7284, SGLT2
Field of Research
Pharmacology & Drug Discovery
Purity
99.42% (May vary between batches)
Solubility
DMSO:255 mg/mL (281.13 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.64 mM)
Smiles
O[C@H]1[C@H] (C2=CC (CC3=CC=C (C4=CC=C (C=C4) F) S3) =C (C=C2) C) O[C@@H] ([C@H] ([C@@H]1O) O) CO.O[C@H]5[C@H] (C6=CC (CC7=CC=C (C8=CC=C (C=C8) F) S7) =C (C=C6) C) O[C@@H] ([C@H] ([C@@H]5O) O) CO.O
Molecular Formula
C48H52F2O11S2
Molecular Weight
907.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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