S1RA
S1RA (E-52862) is a potent and highly selective sigma-1 receptor (σ1R) antagonist with a Ki of 17 nM, exhibiting over 1000-fold selectivity for σ1R versus the sigma-2 receptor (σ2R) . This tool compound is widely used in vitro and in vivo to investigate σ1R function in neuropathic pain, neuroprotection, and psychiatric disorders.
Product Specifications
CAS Number
878141-96-9
Product Name Alternative
E 52862, E52862, E-52862, Inhibitor, inhibit, σ1, S1RA, S-1RA, Sigma receptor, Sigma Receptor, Sigmareceptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.45% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.93 mM) ; DMSO:10 mM
Smiles
Cc1cc (OCCN2CCOCC2) nn1-c1ccc2ccccc2c1
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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