TD-165
TD-165 is a heterobifunctional PROTAC molecule designed to degrade cereblon (CRBN) by recruiting the VHL E3 ubiquitin ligase complex. This tool compound is used in chemical biology and oncology research to study targeted protein degradation mechanisms in both cellular and in vivo models.
Product Specifications
CAS Number
2305936-56-3
Product Name Alternative
CRBN, degrader, Cereblon:20.4 nM (DC50), Cereblon, inhibit, Inhibitor, HEK293T, PROTAC-based, PROTACs, TD 165, TD165, TD-165
Field of Research
Pharmacology & Drug Discovery
Purity
98.80% (May vary between batches)
Solubility
DMSO:40 mg/mL (45.97 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCCCCCCCCCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C=6SC=NC6C) =O) C[C@@H] (O) C4) C (C) (C) C) =O
Molecular Formula
C46H59N7O8S
Molecular Weight
870.07
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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