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2'-Fluorothymidine

2'-Fluorothymidine is a selective substrate for thymidine kinase 2 (TK2), structurally related to thymidine and methyluridine. It is used in vitro and in vivo to study nucleoside metabolism, TK2 activity, and cellular proliferation, particularly in mitochondrial DNA depletion syndromes and oncology research.

Product Specifications

CAS Number

122799-38-6

Product Name Alternative

2'-Deoxy-2'-fluoro-5-Methyluridine, 2'-​Deoxy-​2'-​fluoro-​5-​Methyluridine, 2'-Fluorothymidine

Field of Research

Cell Biology, Molecular Biology

Purity

99.67% (May vary between batches)

Solubility

DMSO:55 mg/mL (211.36 mM)

Smiles

Cc1cn ([C@@H]2O[C@H] (CO) [C@@H] (O) [C@H]2F) c (=O) [nH]c1=O

Molecular Formula

C10H13FN2O5

Molecular Weight

260.22

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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