8-Hydroxyguanine
8-Hydroxyguanine is a major premutagenic lesion generated by oxidative stress, leading to G-T and A-C transversions. It serves as a key biomarker for oxidative damage to both DNA and RNA and is extensively utilized in mutagenesis and carcinogenesis studies, including in vitro and in vivo cancer research models.
Product Specifications
CAS Number
5614-64-2
Product Name Alternative
2-Amino-6,8-dihydroxypurine, 8 Hydroxyguanine, 7,8-dihydro-8-oxoguanine, 8-Hydroxyguanine, Endogenous Metabolite, EndogenousMetabolite, Human Endogenous Metabolite
Field of Research
Metabolism Research
Purity
90.00% (May vary between batches)
Solubility
H2O:3.34 mg/mL (19.98 mM) ; DMSO:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
NC1NC (C2=NC (NC2=N1) =O) =O
Molecular Formula
C5H5N5O2
Molecular Weight
167.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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