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8-Hydroxyguanine

8-Hydroxyguanine is a major premutagenic lesion generated by oxidative stress, leading to G-T and A-C transversions. It serves as a key biomarker for oxidative damage to both DNA and RNA and is extensively utilized in mutagenesis and carcinogenesis studies, including in vitro and in vivo cancer research models.

Product Specifications

CAS Number

5614-64-2

Product Name Alternative

2-Amino-6,8-dihydroxypurine, 8 Hydroxyguanine, 7,8-dihydro-8-oxoguanine, 8-Hydroxyguanine, Endogenous Metabolite, EndogenousMetabolite, Human Endogenous Metabolite

Field of Research

Metabolism Research

Purity

90.00% (May vary between batches)

Solubility

H2O:3.34 mg/mL (19.98 mM) ; DMSO:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

NC1NC (C2=NC (NC2=N1) =O) =O

Molecular Formula

C5H5N5O2

Molecular Weight

167.13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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