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ELX-02 disulfate

ELX-02 disulfate (NB-124 disulfate) is a eukaryotic ribosome-selective glycoside (ERSG) developed as a potential therapeutic for genetic disorders caused by nonsense mutations. It functions as a translational readthrough agent, promoting the incorporation of a near-cognate tRNA at premature stop codons, which has been demonstrated in cellular and animal models of diseases like cystic fibrosis and mucopolysaccharidosis.

Product Specifications

CAS Number

2244622-33-9

Purity

98.00% (May vary between batches)

Smiles

S (=O) (=O) (O) O.O ([C@H]1[C@H] (O[C@H]2O[C@] ([C@@H] (C) O) ([C@@H] (O) [C@H] (O) [C@H]2N) [H]) [C@@H] (N) C[C@@H] (N) [C@@H]1O) [C@@H]3O[C@] ([C@H] (C) N) ([C@@H] (O) [C@H]3O) [H]

Molecular Formula

C19H40N4O14S

Molecular Weight

580.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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