ELX-02 disulfate
ELX-02 disulfate (NB-124 disulfate) is a eukaryotic ribosome-selective glycoside (ERSG) developed as a potential therapeutic for genetic disorders caused by nonsense mutations. It functions as a translational readthrough agent, promoting the incorporation of a near-cognate tRNA at premature stop codons, which has been demonstrated in cellular and animal models of diseases like cystic fibrosis and mucopolysaccharidosis.
Product Specifications
CAS Number
2244622-33-9
Purity
98.00% (May vary between batches)
Smiles
S (=O) (=O) (O) O.O ([C@H]1[C@H] (O[C@H]2O[C@] ([C@@H] (C) O) ([C@@H] (O) [C@H] (O) [C@H]2N) [H]) [C@@H] (N) C[C@@H] (N) [C@@H]1O) [C@@H]3O[C@] ([C@H] (C) N) ([C@@H] (O) [C@H]3O) [H]
Molecular Formula
C19H40N4O14S
Molecular Weight
580.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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