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GBR 12783 dihydrochloride

GBR 12783 dihydrochloride is a potent and selective dopamine transporter (DAT) inhibitor, demonstrating nanomolar IC50 values in rodent striatal synaptosome assays. It has been shown to enhance memory performance and elevate hippocampal acetylcholine release in rat models, supporting its application in neuroscience research related to dopaminergic signaling and cognition.

Product Specifications

CAS Number

67469-75-4

Product Name Alternative

GBR-12783, GBR12783 2HCl, GBR12783 Dihydrochloride, GBR-12783 Dihydrochloride, GBR 12783, GBR 12783 Dihydrochloride, GBR12783

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

97.81% (May vary between batches)

Solubility

DMSO:45 mg/mL (92.69 mM)

Smiles

N1 (CCN (CC1) CC=CC2=CC=CC=C2) CCOC (C3=CC=CC=C3) C4=CC=CC=C4.Cl.Cl

Molecular Formula

C28H34Cl2N2O

Molecular Weight

485.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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