Ciluprevir
Ciluprevir is a potent and selective HCV NS3 protease inhibitor with demonstrated antiviral activity in humans. While highly effective against genotype 1 (Ki=1.5 nM), it shows reduced affinity for genotypes 2 and 3 proteases (Ki=80-90 nM), making it a candidate for research into pan-genotypic antiviral strategies and resistance mechanisms.
Product Specifications
CAS Number
300832-84-2
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
C (O) (=O) [C@]12[C@@] (C1) (/C=C/CCCCC[C@H] (NC (OC3CCCC3) =O) C (=O) N4[C@] (C (=O) N2) (C[C@@H] (OC=5C6=C (N=C (C5) C=7N=C (NC (C) C) SC7) C=C (OC) C=C6) C4) [H]) [H]
Molecular Formula
C40H50N6O8S
Molecular Weight
774.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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