SB 224289
SB 224289 is a centrally active, orally bioavailable selective 5-HT1B receptor antagonist (pKi = 8.2) with at least 60-fold selectivity over related 5-HT1 and 5-HT2 receptor subtypes. It is a valuable research tool for investigating serotonin function in neuropharmacology, widely used in both in vitro binding assays and in vivo behavioral studies.
Product Specifications
CAS Number
180083-23-2
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C (=O) (N1C=2C=C3C4 (COC3=CC2CC1) CCN (C) CC4) C5=CC=C (C=C5) C6=C (C) C=C (C=C6) C=7N=C (C) ON7
Molecular Formula
C32H32N4O3
Molecular Weight
520.62
Storage Conditions
-20°C
Notes
For research use only.
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