Hydronidone
Hydronidone (F-351) is a non-steroidal anti-inflammatory drug (NSAID) and a candidate therapeutic for hepatic fibrosis. Research indicates it exhibits anti-fibrotic activity, reducing collagen deposition in both in vitro hepatic stellate cell models and in vivo rodent models of liver injury.
Product Specifications
CAS Number
851518-71-3
Product Name Alternative
F 351, F351, F-351, Hydronidone
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Stem Cell & Developmental Biology
Purity
99.55% (May vary between batches)
Solubility
DMSO:90 mg/mL (447.27 mM)
Smiles
Cc1ccc (=O) n (c1) -c1ccc (O) cc1
Molecular Formula
C12H11NO2
Molecular Weight
201.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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J2500-10A 10 Blots
JNK1/2, phosphorylated (Thr183, Tyr185) (c-Jun N-terminal Kinase 1, JNK1, JNK, c-Jun N-terminal Kinase 2, JNK2, JNK1A2, JNK21B1/2, JNK-46, JNK-55, Mitogen-activated Protein Kinase 8, MAP Kinase 8, MAPK 8, MAPK8, PRKM8, Mitogen-activated Protein Kinase 9, MAP Kinase 9, MAPK 9, MAPK9, PRKM9, Stress-activated Protein Kinase 1a, SAPK1a, Stress-activated Protein Kinase 1c, SAPK1c, SAPK1, Stress-activated Protein Kinase JNK1, Stress-activated Protein Kinase JNK2)
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