LG100268

LG100268 is a potent, selective, and orally active retinoid X receptor (RXR) agonist with nanomolar activity against RXR-α, -β, and -γ. It has been used in research to study adipocyte differentiation, sexual differentiation in fish models, and modulation of PD-L1 in breast cancer cell lines, demonstrating utility in metabolic and oncology studies.