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Atopaxar

Atopaxar (E5555) is a reversible protease-activated receptor-1 (PAR-1) antagonist that inhibits thrombin-mediated platelet aggregation. It has been studied in preclinical and clinical research for the potential management of acute coronary syndrome and coronary artery disease.

Product Specifications

CAS Number

751475-53-3

Product Name Alternative

Inhibit, platelets, PAR-1, ER-172594-00, Inhibitor, atherothrombotic, Atopaxar, E 5555, E5555, E-5555, receptor-1, receptor, signaling, Protease Activated Receptor (PAR), protease-activated, Protease-Activated Receptor (PAR), Proteaseactivated Receptor, ProteaseactivatedReceptor, thrombin, Thrombin receptors

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.07% (May vary between batches)

Solubility

DMSO:30 mg/mL (56.86 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.79 mM)

Smiles

CCOc1cc2CN (CC (=O) c3cc (N4CCOCC4) c (OC) c (c3) C (C) (C) C) C (=N) c2c (F) c1OCC

Molecular Formula

C29H38FN3O5

Molecular Weight

527.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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