PEGylated Urate Oxidase Enzyme

<strong>PEGylated Urate Oxidase Enzyme</strong>_x000D_ <strong>Catalog number:</strong> B2013079_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 U_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> PEGylated urate oxidase enzyme_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Pegloticase 2021 Aug 16. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–._x000D_ 2: Schlesinger N, Lipsky PE. Pegloticase treatment of chronic refractory gout: Update on efficacy and safety Semin Arthritis Rheum. 2020 Jun;50(3S):S31-S38._x000D_ 3: Pegloticase 2018 May 21. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–._x000D_ 4: Padda IS, Bhatt R, Parmar M. Pegloticase 2022 Nov 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–._x000D_ 5: Dean L, Kane M. Pegloticase Therapy and G6PD Genotype 2020 Oct 1. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012–._x000D_ 6: Botson JK, Tesser JRP, Bennett R, Kenney HM, Peloso PM, Obermeyer K, LaMoreaux B, Weinblatt ME, Peterson J. Pegloticase in Combination With Methotrexate in Patients With Uncontrolled Gout: A Multicenter, Open-label Study (MIRROR) J Rheumatol. 2021 May;48(5):767-774._x000D_ 7: Anderson A, Singh JA. Pegloticase for chronic gout Cochrane Database Syst Rev. 2010 Mar 17;2010(3):CD008335._x000D_ 8: Sundy JS, Baraf HS, Yood RA, Edwards NL, Gutierrez-Urena SR, Treadwell EL, Vázquez-Mellado J, White WB, Lipsky PE, Horowitz Z, Huang W, Maroli AN, Waltrip RW 2nd, Hamburger SA, Becker MA. Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials JAMA. 2011 Aug 17;306(7):711-20._x000D_ 9: Shannon JA, Cole SW. Pegloticase: a novel agent for treatment-refractory gout Ann Pharmacother. 2012 Mar;46(3):368-76._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33750034">10: Khanna PP, Khanna D, Cutter G, Foster J, Melnick J, Jaafar S, Biggers S, Rahman AKMF, Kuo HC, Feese M, Kivitz A, King C, Shergy W, Kent J, Peloso PM, Danila MI, Saag KG. Reducing Immunogenicity of Pegloticase With Concomitant Use of Mycophenolate Mofetil in Patients With Refractory Gout: A Phase II, Randomized, Double-Blind, Placebo-Controlled Trial Arthritis Rheumatol. 2021 Aug;73(8):1523-1532. </a>_x000D_ _x000D_ <strong>Products Related to PEGylated Urate Oxidase Enzyme can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>