5'-O-Tritylthymidine
5'-O-Tritylthymidine is a small molecule inhibitor that disrupts the FAK/Mdm2 interaction, leading to p53 activation and caspase-8 induction. This mechanism promotes cell detachment and apoptosis, making it a useful research tool for studying p53-dependent pathways in breast and colon cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
7791-71-1
Smiles
Cc1cn ([C@H]2C[C@H] (O) [C@@H] (COC (c3ccccc3) (c3ccccc3) c3ccccc3) O2) c (=O) [nH]c1=O
Molecular Formula
C29H28N2O5
Molecular Weight
484.54
Storage Conditions
-20°C
Notes
For research use only.
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