Sparteine

Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor) [1][2].

Product Specifications

CAS Number

[24915-04-6]

Product Name Alternative

Lupinidine

UNSPSC

12352005

Target

NAChR

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sparteine.html

Smiles

[H][C@]1(CN2[C@@]3([H])CCCC2)[C@@](CCCC4)([H])N4C[C@]3([H])C1

Molecular Formula

C15H26N2

Molecular Weight

234.38

References & Citations

[1]Voitenko S, et al. Effect of (+) -sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40 (2) :180-5. |[2]Cook D, et al. The alkaloid profiles of Lupinus sulphureus. J Agric Food Chem. 2009 Feb 25;57 (4) :1646-53.