Sparteine
Product Specifications
UNSPSC Description
Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor)[1][2].
Target Antigen
nAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sparteine.html
Smiles
[H][C@]1(CN2[C@@]3([H])CCCC2)[C@@](CCCC4)([H])N4C[C@]3([H])C1
Molecular Weight
234.38
References & Citations
[1]Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. |[2]Cook D, et al. The alkaloid profiles of Lupinus sulphureus. J Agric Food Chem. 2009 Feb 25;57(4):1646-53.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N9949/Sparteine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N9949/
Clinical Information
No Development Reported
CAS Number
24915-04-6
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