Cis-Tadalafil
Cis-Tadalafil (cis-IC-351) is a stereoisomer of tadalafil and a potent inhibitor of phosphodiesterase 5 (PDE5), exhibiting an IC50 of 90 nM. It serves as a valuable research compound for investigating PDE5 function in vascular biology, with applications in studies of pulmonary arterial hypertension using both cellular and animal models.
Product Specifications
CAS Number
171596-27-3
Product Name Alternative
(-) -Tadalafil (6R ,12aS) diastereomer, (6R ,12aS) -Tadalafil, cis-IC-351, PDE5, Tadalafil (6R ,12aS) diastereomer, Tadalafil EP Impurity A, Tadalafil specified impurity A, Tadalafil, (6R ,12aS), Tadalafil, (6R ,12aS) -
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
≥98% (May vary between batches)
Solubility
DMSO:Soluble
Smiles
CN1CC (=O) N2C (CC3=C (NC4=CC=CC=C34) C2C2=CC3=C (OCO3) C=C2) C1=O
Molecular Formula
C22H19N3O4
Molecular Weight
389.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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