Imipramine
Imipramine is an orally active Fascin1 inhibitor with antidepressant properties that also exhibits antitumor activity. It functions as a potent serotonin transporter blocker (IC50: 32 nM) and induces apoptosis and autophagy in glioma cells. Its neuroprotective and immunomodulatory effects, including inhibition of tumor cell invasion, make it a valuable research tool for studying cancers like glioblastoma and breast cancer, as well as neurological disorders.
Product Specifications
CAS Number
50-49-7
Product Name Alternative
HSDB 3100, HSDB3100, HSDB-3100, Melipramine, fascin 1, Imipramine, Dimipressin, Apoptosis
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.40% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (17.83 mM) ; DMSO:100 mg/mL (356.62 mM)
Smiles
C=1C=CC2=C (C1) N (C=3C=CC=CC3CC2) CCCN (C) C
Molecular Formula
C19H24N2
Molecular Weight
280.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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