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Imipramine

Imipramine is an orally active Fascin1 inhibitor with antidepressant properties that also exhibits antitumor activity. It functions as a potent serotonin transporter blocker (IC50: 32 nM) and induces apoptosis and autophagy in glioma cells. Its neuroprotective and immunomodulatory effects, including inhibition of tumor cell invasion, make it a valuable research tool for studying cancers like glioblastoma and breast cancer, as well as neurological disorders.

Product Specifications

CAS Number

50-49-7

Product Name Alternative

HSDB 3100, HSDB3100, HSDB-3100, Melipramine, fascin 1, Imipramine, Dimipressin, Apoptosis

Field of Research

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Purity

99.40% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (17.83 mM) ; DMSO:100 mg/mL (356.62 mM)

Smiles

C=1C=CC2=C (C1) N (C=3C=CC=CC3CC2) CCCN (C) C

Molecular Formula

C19H24N2

Molecular Weight

280.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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