APY0201
APY0201 is a potent and selective ATP-competitive inhibitor of PIKfyve with an IC50 of 5.2 nM, blocking the synthesis of PtdIns (3,5) P2 from PtdIns3P. It is a valuable research tool for studying lysosomal biology, autophagy, and cellular trafficking in both in vitro and in vivo models.
Product Specifications
CAS Number
1232221-74-7
Product Name Alternative
PIKfyve, Interleukin Related, Interleukin, Fab1, inhibit, Inhibitor, APY 0201, APY0201, APY-0201
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:1 mg/mL (2.42 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.42 mM)
Smiles
Cc1cccc (\C=N\Nc2cc (N3CCOCC3) n3nc (cc3n2) -c2ccncc2) c1
Molecular Formula
C23H23N7O
Molecular Weight
413.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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