Miravirsen
Product Specifications
Product Name Alternative
SPC-3649
UNSPSC Description
Miravirsen (SPC-3649) is a potent miR-122 inhibitor and inhibits the biogenesis of miR-122. Miravirsen is a 15-nucleotide locked nucleic acid-modified phosphorothioate antisense oligonucleotide. Miravirsen inhibits HCV replication. Miravirsen can be used in research of HCV infection[1][2].
Target Antigen
HCV; MicroRNA
Type
Oligonucleotides
Related Pathways
Anti-infection;Epigenetics
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/miravirsen.html
Purity
98.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[Miravirsen]
Molecular Weight
4967.00
References & Citations
[1]Luca F R Gebert, et al. Miravirsen (SPC3649) can inhibit the biogenesis of miR-122. Nucleic Acids Res. 2014 Jan;42(1):609-21.|[2]Elmén J, et, al. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res. 2008 Mar;36(4):1153-62.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132598/Miravirsen-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132598/Miravirsen-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1072874-90-8
Available Sizes
Curated Selection
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