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NS-638

NS-638 is a small nonpeptide molecule with Ca2+-channel blocking properties. K+-stimulated intracellular Ca2+-elevation is blocked with an IC50 value of 3.4 μM.

Product Specifications

CAS Number

150493-34-8

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/NS-638.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : ≥ 34 mg/mL

Smiles

NC1=NC2=CC(C(F)(F)F)=CC=C2N1CC3=CC=C(Cl)C=C3

Molecular Formula

C15H11ClF3N3

Molecular Weight

325.72

Precautions

H315, H319, H335

References & Citations

[1]M?ller A, et al. Pharmacological profile and anti-ischemic properties of the Ca (2+) -channel blocker NS-638. Neurol Res. 1995 Oct;17 (5) :353-60.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

L-type calcium channel

Available Sizes

Frequently Asked Questions

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