Licarin A
Licarin A is a naturally occurring lignan with demonstrated anti-inflammatory activity. It functions by inhibiting the PKCα/βII and p38 MAPK signaling pathways, which subsequently reduces TNF-α and prostaglandin D2 release as well as COX-2 expression. This compound is utilized in vitro for researching inflammation mechanisms in models such as macrophages.
Product Specifications
CAS Number
51020-86-1
Product Name Alternative
(-) -Licarin A, NSC 370989, NSC-370989, NSC370989, Licarin A
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.50% (May vary between batches)
Solubility
DMSO:40 mg/mL (122.55 mM) ; H2O:< 0.1 (insoluble)
Smiles
O (C) C1=C2C ([C@@H] (C) [C@@H] (O2) C3=CC (OC) =C (O) C=C3) =CC (/C=C/C) =C1
Molecular Formula
C20H22O4
Molecular Weight
326.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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