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5'-Amino-5'-deoxyadenosine

5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor with demonstrated antitumor activity against lymphoid malignancies. Its anticancer effects, studied in vitro and in vivo, are primarily mediated through the inhibition of DNA synthesis and the induction of apoptotic cell death.

Product Specifications

CAS Number

14365-44-7

Product Name Alternative

Nsc 238990, NH2dAdo, 5'-Amino-5'-deoxyadenosine, 5'Amino5'deoxyadenosine, 5' Amino 5' deoxyadenosine, Adenosine kinase, Adenosine Receptor, AdenosineReceptor, Apoptosis, DNA

Field of Research

Cell Biology, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery

Purity

95.55% (May vary between batches)

Solubility

DMSO:50 mg/mL (187.79 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.51 mM)

Smiles

O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (CN) [C@H]1O

Molecular Formula

C10H14N6O3

Molecular Weight

266.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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