5'-Amino-5'-deoxyadenosine
5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor with demonstrated antitumor activity against lymphoid malignancies. Its anticancer effects, studied in vitro and in vivo, are primarily mediated through the inhibition of DNA synthesis and the induction of apoptotic cell death.
Product Specifications
CAS Number
14365-44-7
Product Name Alternative
Nsc 238990, NH2dAdo, 5'-Amino-5'-deoxyadenosine, 5'Amino5'deoxyadenosine, 5' Amino 5' deoxyadenosine, Adenosine kinase, Adenosine Receptor, AdenosineReceptor, Apoptosis, DNA
Field of Research
Cell Biology, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
95.55% (May vary between batches)
Solubility
DMSO:50 mg/mL (187.79 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.51 mM)
Smiles
O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (CN) [C@H]1O
Molecular Formula
C10H14N6O3
Molecular Weight
266.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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