R306465
R306465 (JNJ-16241199) is a potent and selective HDAC1 inhibitor (IC50 = 3.3 nM) that induces histone acetylation and apoptosis. It demonstrates broad-spectrum antitumor activity in preclinical studies, supporting its investigation for both solid tumors and hematological malignancies in vitro and in vivo.
Product Specifications
CAS Number
604769-01-9
Product Name Alternative
R306465, R-306465, R 306465, JNJ16241199, JNJ-16241199, JNJ 16241199, HDAC1, Apoptosis
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.46% (May vary between batches)
Solubility
DMSO:5 mg/mL (12.09 mM)
Smiles
O=C (NO) C1=CN=C (N=C1) N2CCN (CC2) S (=O) (=O) C=3C=CC=4C=CC=CC4C3
Molecular Formula
C19H19N5O4S
Molecular Weight
413.45
Storage Conditions
-20°C
Notes
For research use only.
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