Fluvastatin
Fluvastatin is a potent, competitive HMG-CoA reductase inhibitor (IC50: 8 nM) used to lower plasma cholesterol. It also reduces oxidative stress in vascular smooth muscle cells via an Nrf2 pathway, making it a research tool for studying atherosclerosis and cardiovascular disease in both cellular and animal models.
Product Specifications
CAS Number
93957-54-1
Product Name Alternative
Cranoc, Canef, HMGCoAReductase, HMGCoA Reductase, HMG-CoA Reductase (HMGCR), Lescol, Fluvastatin, Vastin, XU-62320, XU62320, XU 62320
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.94% (May vary between batches)
Solubility
H2O:Insoluble; DMSO:252.5 mg/mL (613.65 mM)
Smiles
C (=C/[C@@H] (C[C@@H] (CC (O) =O) O) O) \C1=C (C=2C (N1C (C) C) =CC=CC2) C3=CC=C (F) C=C3
Molecular Formula
C24H26FNO4
Molecular Weight
411.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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