Sivelestat sodium
Sivelestat sodium is a potent and selective human neutrophil elastase inhibitor. It has been shown to ameliorate sepsis-induced myocardial dysfunction in research models by activating the PI3K/AKT/mTOR pathway, supporting its investigation for conditions like acute lung injury and acute respiratory distress syndrome.
Product Specifications
CAS Number
150374-95-1
Product Name Alternative
Sivelestat sodium, Sivelestat sodium salt, EI546 sodium, EI 546 sodium, LY 544349, LY544349, LY-544349, LY544349 sodium, LY-544349 sodium, ONO5046, ONO-5046, ONO5046 sodium, ONO 5046, ONO 5046 sodium
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.23 mM) ; DMSO:80 mg/mL (175.27 mM)
Smiles
O=C (CNC (C1=C (NS (=O) (C2=CC=C (C=C2) OC (C (C) (C) C) =O) =O) C=CC=C1) =O) [O-].[Na+]
Molecular Formula
C20H21N2NaO7S
Molecular Weight
456.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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