Prostratin
Prostratin is a potent, orally bioavailable PKC activator (Ki=12.5 nM) that induces NF-κB and HIV expression. It exhibits anti-leukemic activity by inhibiting AML cell growth and enhancing cytarabine-induced differentiation, and it suppresses KRAS-mutated tumor growth through KRAS phosphorylation.
Product Specifications
CAS Number
60857-08-1
Product Name Alternative
12-Deoxyphorbol 13-Acetate; dPAc
Field of Research
Neuroscience
Purity
>98%
Bioactivity
PKC activator; Promotes neuro-regeneration
Form
Wax
Solubility
Soluble in DMSO (up to 30 mg/ml) .
Smiles
O (C (C) =O) [C@@]12[C@@] (C1 (C) C) ([C@]3 ([C@] (O) ([C@H] (C) C2) [C@]4 ([C@] (O) (CC (CO) =C3) C (=O) C (C) =C4) [H]) [H]) [H]
Molecular Formula
C22H30O6
Molecular Weight
390.47
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
13-O-Acetyl-12-deoxyphorbol
Available Sizes
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