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5,15-DPP

5,15-Diphenylporphyrin (5,15-DPP) is a small molecule inhibitor that selectively targets the STAT3-SH2 domain, exhibiting potent activity against STAT3 (IC50 = 0.28 μM) with significantly lower potency against STAT1. This antagonist is a valuable research tool for studying STAT3-driven signaling pathways in cancer and inflammation, applicable in both cellular and biochemical assays.

Product Specifications

CAS Number

22112-89-6

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Smiles

C1cc2nc1cc1ccc ([nH]1) c (-c1ccccc1) c1ccc (cc3ccc ([nH]3) c2-c2ccccc2) n1

Molecular Formula

C32H22N4

Molecular Weight

462.54

Storage Conditions

-20°C

Notes

For research use only.

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