MG-115
MG-115 (Z-LL-Nva-CHO) is a potent, reversible proteasome inhibitor that selectively targets the chymotrypsin-like activity, with K i values of 21 nM and 35 nM for the 20S and 26S proteasome, respectively. This compound is widely used in cancer research to study proteasome function, p53-dependent apoptosis, and cellular mechanisms in both in vitro and in vivo models.
Product Specifications
CAS Number
133407-86-0
Product Name Alternative
MG 115, MG115, MG-115, 26S proteasome, 20S proteasome, Z-LL-Nva-CHO
Field of Research
Cell Biology, Protein Biochemistry
Purity
97.10% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:4 mg/mL (8.67 mM) ; DMSO:45 mg/mL (97.49 mM)
Smiles
CCCC (NC (=O) C (CC (C) C) NC (=O) C (CC (C) C) NC (=O) OCc1ccccc1) C=O
Molecular Formula
C25H39N3O5
Molecular Weight
461.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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