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IWP-3

IWP-3 is a potent small molecule Wnt inhibitor that blocks Wnt protein palmitoylation, suppressing oncogenic signaling. It reduces viability in cancer cell lines like MG63 and is applied in myeloma and other cancer research, supporting both in vitro and in vivo studies of Wnt pathway dysregulation.

Product Specifications

CAS Number

687561-60-0

Product Name Alternative

Beta-catenin, betacatenin, bcatenin, IWP3, IWP-3, IWP 3, βcatenin, Wnt/β-catenin, Wnt/betacatenin, Wnt/b-catenin, Wnt

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

98.00% (May vary between batches)

Solubility

DMSO:15 mg/mL (30.95 mM)

Smiles

Cc1ccc2nc (NC (=O) CSc3nc4CCSc4c (=O) n3-c3ccc (F) cc3) sc2c1

Molecular Formula

C22H17FN4O2S3

Molecular Weight

484.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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