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NVP DPP 728 dihydrochloride

NVP-DPP728 is a potent and reversible nitrile-based inhibitor of dipeptidyl peptidase IV (DPP-IV) with a Ki of 11 nM. By blocking DPP-IV-mediated GLP-1 degradation, it enhances glucose-stimulated insulin secretion. This inhibitor is a valuable research tool for studying type 2 diabetes mechanisms in both in vitro enzymatic assays and in vivo models.

Product Specifications

CAS Number

247016-69-9

Field of Research

Protein Biochemistry

Smiles

C (CNCCNC1=CC=C (C#N) C=N1) (=O) N2[C@H] (C#N) CCC2

Molecular Formula

C15H18N6O

Molecular Weight

298.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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